Selected Publications

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

- Claude Bernard -


Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction

Razin T, Melamed-Book N, Argaman J, Galin I, Lowy Y, Anuka E, Naftali-Shani N, Kandel-Kfir M, Garfinkel BP, Brielle S, Granot Z, Apte RN, Conway SJ, Molkentin JD, Kamari Y, Leor J, Orly J.

J Mol Cell Cardiol.

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

Parhi L, Alon-Maimon T, Sol A, Nejman D, Shhadeh A, Fainsod-Levi T, Yajuk O, Isaacson B, Abed J, Maalouf N, Nissan A, Sandbank J, Yehuda-Shnaidman E, Ponath F, Vogel J, Mandelboim O, Granot Z, Straussman R, Bachrach G.

Nat. Commun.


Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Hsu BE, Tabariès S, Johnson RM, Andrzejewski S, Senecal J, Lehuédé C, Annis MG, Ma EH, Völs S, Ramsay L, Froment R, Monast A, Watson IR, Granot Z, Jones RG, St-Pierre J, Siegel PM.

Cell Rep

Targeted siRNA Nanoparticles for Mammary Carcinoma Therapy

Ben-David-Naim M, Dagan A, Grad E, Aizik G, Nordling-David MM, Morss Clyne A, Granot Z, Golomb G.

Cancers (Basel)

Neutrophils as a Therapeutic Target in Cancer

Granot Z.

Frontiers in Immunology

Neutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity

 Sionov RV, Fainsod-Levi T, Zelter T, Polyansky L, Pham CT and Granot Z.


TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

Gershkovitz M, Fainsod-Levi T, Zelter T, Sionov RV and Granot Z.

Cancer Immunology Immunotherapy


Microenvironmental cues determine tumor cell susceptibility to neutrophil cytotoxicity

Gershkovitz M, Fainsod-Levi T, Khawaled S, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Fridlender ZG and Granot Z.

Cancer Research

TRPM2 mediates neutrophil killing of disseminated tumor cells

Gershkovitz M, Caspi Y, Fainsod-Levi T, Katz B, Michaeli J, Khawaled S, Lev S, Polyansky L, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Mori Y, Karni R, Fridlender ZG, Binshtok AM and Granot Z.

Cancer Research


The regulation of pre-metastatic niche formation by neutrophils

Jablonska J, Lang S, Sionov RV and Granot Z.


Tumor-associated neutrophils induce apoptosis of non-activated CD8 T-cells in a TNFα and NO-dependent mechanism, promoting a tumor-supportive environment.

Michaeli J, Shaul ME, Mishalian I, Hovav AH, Levy L, Zolotriov L, Granot Z and Fridlender ZG.


Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection.

Isaacson B, Hadad T, Glasner A, Gur C, Granot Z, Bachrach G and Mandelboim O.

Cell Rep.

Always Look On the Bright Side: Anti-Tumor Functions of Neutrophils.

Völs S, Sionov RV and Granot Z.

Curr Pharm Des

Neutrophil, quo vadis?

Jablonska J and Granot Z.

J Leukoc Biol.

The diversity of circulating neutrophils in cancer.

Mishalian I, Granot Z and Fridlender ZG.



Macrophages and Neutrophils: Regulation of the Inflammatory Microenvironment in Autoimmunity and Cancer.

Rahat MA, Coffelt SB, Granot Z, Muthana M and Amedei A.

Mediators Inflamm